Isabella from The Promised Neverland obeys out of fear and survival, trapped in a system that pits her against the children she's raised. Her compliance is born from desperation, evoking empathy for her plight.

Gentle Criminal of My Hero Academia pursues his misguided dreams of heroism through villainy, driven by a desire to be acknowledged. His aspiration, coupled with his gentle demeanour, makes him oddly endearing.

Queen Beryl's unrequited love for Endymion in Sailor Moon fuels her descent into darkness. Her tragic love story adds depth to her character, eliciting sympathy despite her malevolent actions.

Reiner Braun from Attack on Titan wrestles with guilt and duty, torn between loyalty to his homeland and sympathy for his enemies. His inner conflict and sense of duty make him a complex and sympathetic antagonist.

Yako in Toilet-Bound Hanako-kun struggles with feelings of exclusion, leading to his antagonistic behaviour. His loneliness and desire to belong make him a sympathetic figure in the series.

Izanami of Noragami seeks companionship, resorting to extreme measures that cast her as a villain. Her loneliness and longing for connection make her motivations relatable and poignant.

Scar's quest for vengeance in Fullmetal Alchemist: Brotherhood is fueled by the genocide of his people. His tragic backstory and moral conflict evoke sympathy as he struggles with his path of retribution.

Cancer Cell from Cells At Work didn't choose its existence; it was inadvertently created. Its plight as an unintended threat to the body's balance adds a layer of sympathy to its role as a villain.

Damian Desmond, from Spy x Family, seeks attention due to his lonely upbringing in espionage. His antics to gain recognition are a poignant reflection of his yearning for familial warmth, making him a uniquely sympathetic villain.

Shishio Tsukasa of Dr. Stone rebels against authority to create a world free from the constraints of modern civilisation. His vision for freedom, though extreme, resonates with those disillusioned by society's norms.