Asthma or depression may raise kidney failure risk later in life: Study

Asthma and depression are conditions most people see as separate health issues, but new research shows they may have a surprising connection to kidney health. A study published in the Journal of the American Geriatrics Society followed nearly 3,100 older adults over 15 years to examine how chronic illnesses affect kidney function decline. The findings revealed that individuals with conditions such as asthma or depression were more likely to experience accelerated kidney decline, especially when combined with other chronic diseases like diabetes or hypertension.

This discovery highlights the importance of viewing health holistically. While asthma affects the airways and depression impacts mental well-being, their indirect role in long-term kidney health cannot be ignored. The study suggests that multiple chronic conditions create a cumulative strain on the body, increasing the risk of kidney damage over time.
In this article, we break down the study’s key findings, explain why these links matter, and explore how people living with asthma or depression can take steps to protect their kidney health.




Asthma and kidney failure risk explained

Asthma is commonly thought of as a condition affecting the lungs, but its impact may go beyond breathing difficulties. The study found that adults with a history of asthma had a higher chance of kidney function decline when compared to those without it. Chronic inflammation, which plays a central role in asthma, may indirectly affect other organs, including the kidneys.

Over time, inflammatory processes can damage blood vessels and increase the body’s vulnerability to systemic diseases. Since kidneys rely on healthy blood circulation to filter waste, long-term inflammation may accelerate their deterioration. This explains why asthma, though not directly related to kidney disease, could be an important risk factor.




Depression and its link to kidney health
Depression is often underestimated as a physical health risk, but the study shows its potential impact on the kidneys. Individuals with depression were more likely to experience faster kidney decline compared to those without the condition.

This can be explained through several mechanisms. Depression is strongly linked to hormonal changes, higher stress levels, and an increase in inflammatory markers. It may also lead to lifestyle habits such as poor diet, lack of exercise, smoking, or irregular medical check-ups, which further contribute to kidney damage. Taken together, these factors underline why depression must be recognised as a medical as well as psychological concern.




How multimorbidity increases kidney failure risk
One of the strongest findings of the study was that multimorbidity, or the presence of multiple chronic conditions, accelerates kidney decline. When illnesses such as asthma, depression, diabetes, and hypertension coexist, they interact in ways that place additional strain on kidney function.

For example, high blood pressure damages the kidney’s blood vessels, while diabetes raises blood sugar levels that harm kidney tissues. If these are combined with inflammatory conditions like asthma or lifestyle-related risks associated with depression, the likelihood of kidney failure rises sharply.

This highlights the importance of screening and regular monitoring for individuals with multiple health conditions, even if they do not currently show signs of kidney disease.




Why the asthma and depression study matters for kidney health and public health

The findings are not just about individual health but also about public health planning. With an ageing global population, chronic conditions are becoming more common. Understanding how seemingly unrelated illnesses like asthma and depression influence kidney decline can help shape preventive care strategies.

Healthcare providers can use this knowledge to encourage earlier kidney function tests, create personalised treatment plans, and provide lifestyle guidance to at-risk groups. At the same time, raising awareness ensures that patients themselves take an active role in monitoring their long-term health.




Steps to protect kidney health if you have asthma or depression

Living with asthma or depression does not mean kidney failure is inevitable. The key is prevention and early management. Some recommended steps include:

• Regular kidney function tests, especially if you also have conditions like diabetes or hypertension.
• Following an anti-inflammatory diet rich in fruits, vegetables, whole grains, and omega-3 fatty acids.
• Staying physically active to support overall health and reduce stress.

Managing asthma symptoms effectively with prescribed medication and routine check-ups.

Seeking support and treatment for depression to avoid lifestyle patterns that can harm the kidneys.

Staying hydrated and avoiding excessive alcohol or high-salt diets.

These measures not only support kidney health but also improve overall well-being.

The study published in the Journal of the American Geriatrics Society provides strong evidence that conditions like asthma and depression may contribute to kidney decline later in life. The risk is particularly high when multiple chronic illnesses are present, making multimorbidity a serious concern for long-term kidney health.

For individuals and healthcare systems, the message is clear. Monitoring kidney function in patients with chronic conditions is not optional but essential. By understanding these hidden links and taking preventive measures, it is possible to reduce the risk of kidney failure and ensure healthier ageing.




Disclaimer: This article is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider regarding any medical condition or lifestyle change.




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